p 13: Lesson 3 Bell work
What did we figure out happens when people with DMD exercise compared to when people with healthy muscles exercise?
p 14: Muscles Flow Map
We colored and labeled a visual of a muscle and created a flow map of different parts of a muscle tissue
p 15: Muscle Structure Fill-in-the-Blank
Get template from teacher if necessary
p 16: Proteins
We copied and answered the questions below:
- When you are trying to grow muscle, what are you supposed to eat a lot of?
- Based on what we know about what happens to muscles when we exercise, why do you think eating protein is important?
- Is there only one protein?
- What are some examples of proteins we have talked about so far?
p 17: Examining Different Types of Muscle Proteins
Read and annotate the data on your notebook.
| Muscle Proteins | Healthy Muscle | DMD Muscle |
| Actin | 12-15% | 12-15% |
| Myosin | 16-18% | 16-18% |
| Dystrophin | 8-10% | 0-1% |
| Creatine Kinase | 2-4% | 8-10% |
- Dystrophin is almost nonexistent or very low in people with DMD
- Creatine Kinase is a lot higher in people with DMD.
Why do you think this might be happening? Explain.
p 18: Investigating the Proteins
| Dystrophin | Creatine Kinase |
Complete the table above using notes from the video below:
p 19: Dystrophin & Creatin Kinase Discussion
Copy and answer the questions below:
1. What role does dystrophin play in muscle contraction?
2. Why might lacking dystrophin affect muscle function in patients with DMD?
3. What are some ideas for why the data showed CK to be higher in individuals with DMD?
4. Why might doctor’s measure CK in patients with DMD?
5. How did the DMD muscle contract differently when compared to the healthy muscle?
6. What role does calcium play in patients with DMD?
p 20: The Life of People with DMD
Write a paragraph that starts with the sentence below:
Muscular Dystrophy is a degenerative disorder.
Complete the paragraph by answering the questions below in order.
- What does that mean for people with DMD? (will they get better or worse?)
- Is there anything that we can do?
- Do you think people with DMD should do physical therapy? Explain where you stand
p 21: Harvest Discussion
Students did a world cafe discussion then copied and answered the questions below:
- What do we know about DMD so far?
- What are the pros/cons of a person with DMD doing physical therapy?
- Should people with DMD be allowed to play (run, exercise) when they are young?