digital discussions

The Conversations Continue

Kelly and Penny Kittle pick up where they left off one year after the start of their last video discussion series: Teaching In a Time of Uncertainty. In this new series, Kelly and Penny will explore some of the interesting thinking and ideas to emerge from a year filled with challenges and change. Once you’ve watched, be sure to check out related resources on Padlet.

Kati Kariko Helped Shield the World From the Coronavirus

By Gina Kolata

She grew up in Hungary, daughter of a butcher. She decided she wanted to be a scientist, although she had never met one. She moved to the United States in her 20s, but for decades never found a permanent position, instead clinging to the fringes of academia.

Now Katalin Kariko, 66, known to colleagues as Kati, has emerged as one of the heroes of Covid-19 vaccine development. Her work, with her close collaborator, Dr. Drew Weissman of the University of Pennsylvania, laid the foundation for the stunningly successful vaccines made by Pfizer-BioNTech and Moderna.

For her entire career, Dr. Kariko has focused on messenger RNA, or mRNA — the genetic script that carries DNA instructions to each cell’s protein-making machinery. She was convinced mRNA could be used to instruct cells to make their own medicines, including vaccines.

But for many years her career at the University of Pennsylvania was fragile. She migrated from lab to lab, relying on one senior scientist after another to take her in. She never made more than $60,000 a year.